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Information provided on personal blogs and commercial websites advises fitness and bodybuilding enthusiasts to supplement with ostarine at dose ranges from 10 mg to 30 mg for at least 12 weeks. As noted by the Food and Drug Administration, ostarine is indicated for use as a dietary supplement for the treatment of severe hypertriglyceridemia, where it acts to stimulate fatty acid oxidation in the body and to counteract the adverse effects of diet-induced hyperlipidemia (22). In patients with coronary heart disease, doses in the upper range of 10 mg have repeatedly been associated with a decreased risk of mortality (23–25), hgh kaufen. In a meta-analysis of randomized controlled trials in patients with congestive heart failure or atrial fibrillation treated for hypertension or diabetes, a dose range of 2.4 mg to 9.6 mg per day was associated with a 30% reduction in mortality with an increased risk of 0.2 to 1.9 events per 10 000 person-years. (26), genotropin wieviel mg einheiten 12. Recent evidence suggests that oral ostarine has the potential to improve glycemic control in both type 2 and type 1 diabetes mellitus. For this reason, it is recommended that clinical trials of ostarine for treatment of type 2 diabetes mellitus should begin early in the course of diabetes management and that additional trials in the prevention of hypertension include ostarine as an adjunct therapy when the benefit is most expected. Several reviews have provided additional data implicating ostarine to benefit glucose metabolism and glucose control in patients with type 2 diabetes, genotropin 12 mg wieviel einheiten. In an initial review, R. W, somatropin bodybuilding. Hines (27) reported that a dose of 7 mg/kg/day ostarine could increase glucose output to <10 mMglucose by increasing GLUT1 activity and increase insulin sensitivity in diabetic rats that were fed 7 mg/kg ostarine orally for 11 wk, and after treatment there was reduced glucose output and improved glycemia. In a subsequent review, L. L. Ainsworth and S. M. Fenton (28) observed that a dose of 30 mg/kg ostarine per day over 12 wk in diabetics with hyperinsulinemia increased total plasma cholesterol and triglycerides, reduced hepatic triglyceride synthesis, and improved glucose uptake, insulin sensitivity, and liver function. After 13 mo of treatment there was a reduction in serum total cholesterol concentrations from a baseline value of 2, hgh kaufen.6 mmol/L to 2, hgh kaufen.1 mmol/L, improved LDL cholesterol concentrations by 0, hgh kaufen.3 mmol/L, and decreased triglycerides by 4, hgh kaufen.8 mmol/L, hgh kaufen. In a subsequent meta-analysis, A. Al-Qasim and S.